Suppose that \(u = u(t)\) is a solution to
\begin{align*}
x' & = f(t, x)\\
x(t_0) & = x_0,
\end{align*}
on some interval \(I\) containing \(t_0\text{.}\) Since \(u\) is continuous on \(I\) and \(f\) is continuous on \(R\text{,}\) the function \(F(t) = f(t, u(t))\) is also continuous on \(I\text{.}\) Integrating both sides of \(u'(t) = f(t, u(t))\) and applying the Fundamental Theorem of Calculus, we obtain
\begin{equation*}
u(t) - u(t_0) = \int_{t_0}^t u'(s) \, ds = \int_{t_0}^t f(s, u(s)) \, ds
\end{equation*}
Since \(u(t_0) = x_0\text{,}\) the function \(u\) is a solution of the integral equation.
Conversely, assume that
\begin{equation*}
u(t) = x_0 + \int_{t_0}^t f(s, u(s)) \, ds.
\end{equation*}
If we differentiate both sides of this equation, we obtain \(u'(t) = f(t, u(t))\text{.}\) Since
\begin{equation*}
u(t_0) = x_0 + \int_{t_0}^{t_0} f(s, u(s)) \, ds = x_0,
\end{equation*}
the initial condition is fulfilled.